Gilson Connect
Fraction collection can be conducted in a variety of manners. Most commonly, however, fractions are collected either based on a simple function of time or more complex parameters set off by the signals from your detectors. Learn more in our helpful video, which highlights 8 common questions about fraction collection.
Preparative high performance chromatography (prep HPLC or LC) plays a crucial role in many industries. It is used to isolate and purify desired compounds, removing impurities and contaminants that can affect the quality and performance of the end product. In this video, we answer your questions about prep HPLC and how it can fit into your lab's purification workflows.
In high performance liquid chromatography (HPLC), the selection of an appropriate mode of detection is vital to the success of any separation. To this end, there are numerous choices one might consider when configuring a new HPLC setup. Mass spectrometry (MS) is an alternative method of detection and identification that is much more robust than UV. Here, we describe how the VERITY 1920 Mass Spectrometer allows for MS detection capabilities at an affordable price for HPLC fraction collection.
Fractionation, or the separation of a mixture of molecules into different parts or “fractions,” helps scientists understand and/or use a complex solution. Collecting and isolating individual fractions from a mixture can enable many downstream applications as specific molecules can be separated based on physical and chemical properties. In this article, we explore the basics of fraction collection, including applications, parameters, and available solutions for your lab.
Sample integrity is vital for accurate, trustworthy results and it can be affected by all stages of liquid handling, from pipetting to transport. Taking actions to improve pipetting and pipette storage, the lab environment, and sample storage and transport can protect your sample integrity and give you trustworthy results – learn more here.
Preparative chromatography, a method used to separate and purify target compounds from complex mixtures, plays a crucial role in the chemical and pharmaceutical industries. In either industry, preparative chromatography has roles in the early stages of drug development, pilot studies, and process development. In this article, you'll learn how we provide support throughout this process and enable our customers and partners to achieve their purification goals from the milligrams to the kilogram scale.
When choosing a high performance liquid chromatography (HPLC) system, it's important to consider how your future needs may evolve from your current needs. In this article, you’ll learn about the advantages of modular HPLC systems when it comes to current experimental needs and how the ability to swap out HPLC components safeguards the future of your system and your research.
Preparative high performance liquid chromatography (HPLC) is a well-established method for purifying target compounds. Method development is usually done at a smaller scale to define sufficient resolution between the peaks without wasting large amounts of sample. It is common to scale-up the purification from a smaller column to a larger preparative one - learn more in this technical note.
How do you know you’re pipetting the volume you intend? Would you trust the results you’re getting if you didn’t know your pipettes were calibrated properly? Fortunately, there are standards that pipette manufacturers and calibration services follow so that you know you’re pipetting the correct volumes. Read more here.
Regular maintenance and service of your pipette ensures reliable results. Refer to the MyPIPETMAN Two-Minute Inspection video for a walk through of basic pipette performance evaluation. Good routine maintenance helps prevent costly repairs.
